Category Longevity

MOTS-C: The Complete Guide

MOTS-C is unlike anything else in this guide series — a peptide encoded in mitochondrial DNA, discovered in 2015. This guide covers its AMPK-activation mechanism, the real story behind the CB4211 analog often confused with it, why cycling matters, and the practical dosing math for a genuinely novel compound.

NAD+: The Complete Guide

NAD+ IV therapy is available at thousands of clinics worldwide — and a 2025 systematic review found zero completed outcomes trials for injectable use, for any of the claims it's marketed on. This guide covers what's actually been shown, the real mechanism behind the flush, and how it compares to oral precursors.